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Method of treating blood plasma to remove low density lipoproteins and very low density lipoproteins selectively
Method of treating blood plasma to remove low density lipoproteins and very low density lipoproteins selectively
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机译:治疗血浆以选择性去除低密度脂蛋白和极低密度脂蛋白的方法
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摘要
A process is described for removing low density and very low density lipoproteins from blood plasma or serum and recovering the plasma or serum in a physiologically acceptable form. The method involves in a preferred embodiment passing plasma or serum through a cationic ion exchanger equilibrated with a physiologically acceptable saline solution. The ion exchanger is a water insoluble hydrophilic, water swellable cross-linked regenerated or microgranular cellulose matrix substituted with hydroxy C2-C4 alkyl group. The ion exchanger capacity is provided by sulphate groups substituted with from 2 to 6 meq/g. The take up of low density lipoproteins is enhanced by recycling the plasma through the column.
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