Cloned cardionatrin cDNA, cleaved cardionatrin cDNA and cardionatrin precursors, their preparation, corresponding plasmids and microorganisms comprising said plasmid

摘要

A novel cloned cardionatrin cDNA is produced from rat atria. The cardionatrin cDNA codes for a pro-cardionatrin precursor, which contains cardionatrin 1-28 at its C-terminal end. Also provided are methods of making the cloned cardionatrin cDNA, pro-cardionatrin, a cleaved cDNA which codes exclusively for the cardionatrin 1-28, corresponding plasmids and transformed microorganisms.