PROCESS FOR THE PREPARATION OF ISOSILYBIN-FREE SILIBININ AND SILIBININE-CONTAINING DRUGS

摘要

According to the invention, ISOSILYBINE-FREE SILIBININ IS PREPARED FROM DRY FRUITS OF SILYBUM MARIANUM L. GAERTN. FROM WHICH A BROWN POWDER IS EXTRACTED, FOLLOWING WHICH SILIBININ IS SEPARATED IN SEVERAL STEPS INVOLVING TREATMENT WITH METHANOL AND ETHYL ACETATE, UNDER WELL DETERMINED CONDITIONS. / P / p P APPLICATION TO THE PREPARATION OF MEDICAMENTS FOR THE TREATMENT AND PREVENTION OF HEPATIC DISORDERS.