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Perfluoro-1-azatricyclic amines as blood substitutes

机译:全氟-1-氮杂三环胺作为血液替代品

摘要

A novel compound of the formula, ##STR1## wherein k is zero or an integer of 1 to 2, j is an integer of from 1 or 3, l and m are each zero or an integer of from 1 to 3, and n is an integer of from 1 to 4, the rings A, B and C being optionally substituted with at least one trifluoromethyl group or tetrafluoroethyl group is prepared by reacting the perhydro compound corresponding thereto with fluorine. The compound is useful as a material capable of carrying oxygen in an aqueous emulsion for lifesaving a patient suffering from massive hemorrhage and for preserving internal organs in transplantation.
机译:式的新型化合物,其中k为0或1至2的整数,j为1或3的整数,l和m分别为0或1至3的整数,和n为1〜4的整数,通过使与其相对应的过氢化合物与氟反应,制备环A,B和C任选被至少一个三氟甲基或四氟乙基取代。该化合物可用作能够在水性乳剂中携带氧气的材料,以挽救遭受大出血的患者并在移植中保存内部器官。

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