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PREPARATION OF NON TOXIN IMMUNOGENIC PRESCRIPTION FOR PERTUSSIS TOXIN AND MANUFACTURE OF PERTUSSIS VACCINE
PREPARATION OF NON TOXIN IMMUNOGENIC PRESCRIPTION FOR PERTUSSIS TOXIN AND MANUFACTURE OF PERTUSSIS VACCINE
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机译:百日咳毒素的非毒素免疫原性制备及百日咳疫苗的生产
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摘要
The present invention provides a method of preparing a substantially non-toxic immunogenic preparation of pertussis toxic comprising treatment of pertussis toxin with a carbodiimide. The preparation may be used for vaccination against whooping cough as well as making vaccines for use in immunization against whooping cough. Desirably the pertussis toxin is treated in the form of an intimate admixture with filamentous.
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