METHOD FOR PREPARING Aqueous Injectable Solutions of SULFAMETHOXAZOLE OR SULFADOXIN AND A SULPHONAMIDE POTENTIATOR

摘要

Aqueous parenteral sulfonamide solutions comprising water, from 10 to 20% w/v based on the total volume of solution of sulfamethoxazole or sulfadoxine, from 3 to 5% w/v based on the total volume of solution of trimethoprim, and from 60 to 80% w/v based on the total volume of solution of 2-pyrrolidone. Polyvinylpyrrolidone may also be present having an m.w. of from 5000 - 100,000.