FOERFARANDE Foer FRAMSTAELLNING AV ETT PULVER, SOM KAN REKONSTITUERAS by the addition AV WATER Foer ERHAOLLANDE AV EN Farmaceutisk SUSPENSION AV BACAMPICILLINSYRAADDITIONSSALTMIKROKAPSLAR I ETT VATTENSUSPENSIONMEDIUM.

摘要

A novel formulation of bacampicillin for oral administration is disclosed. Microcapsules comprising an acid addition salt of bacampicillin coated with a mixture of ethyl cellulose:water-soluble or water-permeable filler material are suspended in a buffered vehicle having a pH of at least 6.9. The novel suspension is characterized by palatable taste, surprisingly good stability and enhanced bioavailability after oral administration. The novel suspension is well suited for multiple dose oral administration. The preferred filler material is hydroxypropyl cellulose.