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This metabolite of streptomyces and its application as a veterinary medicinal product

机译:链霉菌的这种代谢产物及其在兽药中的应用

摘要

The invention relates to a novel metabolite, M.139603, of the empirical formula C35H53O8Na, which is obtained from the aerobic fermentation of a novel Streptomyces species, NCIB 11426, and to the corresponding free acid form thereof, C35H54O8. M.139,603 reduces the proportion of methane produced by the "digestion" of food in the rumen of ruminant animals and increases the proportion of propionate to acetate in the rumen contents. The compound is therefore useful for increasing the growth rate of ruminant animals, and/or for increasing their efficiency of food conversion. The compound also possesses activity against Gram positive micro-organisms, and against coccidia, for example Eimeria tenella.
机译:本发明涉及经验式C35H53O8Na的新型代谢物M.139603,其从新型链霉菌属物种NCIB 11426的需氧发酵获得,并且涉及其相应的游离酸形式C35H54O8。 M.139,603降低了反刍动物瘤胃中食物“消化”产生的甲烷的比例,并提高了瘤胃内容物中丙酸酯与乙酸酯的比例。因此,该化合物对于提高反刍动物的生长速度和/或提高其食物转化效率是有用的。该化合物还具有抗革兰氏阳性微生物和球菌的活性,例如艾美球虫。

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