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DERIVATIVES OF 4-OH QUINOLINE CARBOXYLIC ACID SUBSTITUTED AT POSITION 2 BY A DIHYDROXYLATED GROUP POSSIBLY ETHERIFIED OR ESTERIFIED,THE PROCESS AND THE INTERMEDIATES FOR THEIR PREPARATION,THEIR APPLICATION AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM
DERIVATIVES OF 4-OH QUINOLINE CARBOXYLIC ACID SUBSTITUTED AT POSITION 2 BY A DIHYDROXYLATED GROUP POSSIBLY ETHERIFIED OR ESTERIFIED,THE PROCESS AND THE INTERMEDIATES FOR THEIR PREPARATION,THEIR APPLICATION AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM
Compounds of formula (I): IMAGE in which X at 5, 6, 7 or 8 is H, halogen, (C1-5) alkyl, (C1-4) alkoxy, -CF3, -SCF3, -OCF3, R1 is phenyl optionally substituted by at least OH, (C1-5) alkyl, (C1-4) alkoxy, CF3, NO2, halogen or a heterocyclic radical optionally substituted by a (C1-4) alkyl radical, R2 and R3 which are identical or different are H, (C1-4) alkyl, aryl, -C(:O)-R5, R5 being (C1-4) alkyl or aryl. R4 is H, (C1-4) alkyl or aryl, and their addition salts with acids and bases.
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机译：式（I）的化合物：，其中在5、6、7或8处的X为H，卤素，（C1-5）烷基，（C1-4）烷氧基，-CF3，-SCF3，-OCF3，R1是任选至少被OH，（C1-5）烷基，（C1-4）烷氧基，CF3，NO2，卤素或任选被（C1-4）烷基取代的杂环基的苯基，R2和R3相同或不同的是H，（C 1-4）烷基，芳基，-C（∶O）-R 5，R 5为（C 1-4）烷基或芳基。 R 4是H，（C 1-4）烷基或芳基，以及它们与酸和碱的加成盐。
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