AMINOGLYCOSIDE NOR-CHOLANIC DERIVATIVES

摘要

PCT No. PCT/EP87/00006 Sec. 371 Date Oct. 29, 1987 Sec. 102(e) Date Oct. 29, 1987 PCT Filed Jan. 7, 1987 PCT Pub. No. WO87/04166 PCT Pub. Date Jul. 16, 1987. IMAGE I Compounds I (either R1=OH, C1-C4 alkoxy and R2=H, C1-C4 alkyl, or R1+R2=a chemical bond; R3=an aminodeoxy or aminodideoxy or aminotrideoxy sugar residue of the D and L series, the glycosidic linkage being alpha or beta : and either R4=OH and R5=H or R4+R5=a chemical bond) and their pharmaceutically acceptable salts are useful as antihypertensive agents. Their preparation and use as well as pharmaceutical compositions containing them are also described.