2 - alkyl - or - aralkyltio - 1 - cykloalken - 1 - karboxamider and their sulfoxides, seen for their framstellning and their anvendning for synthesis of tri - and 4.5 - tetrametylen - 4 - isotiazolin - 3 million

摘要

A process for preparing a 4,5-tri or tetramethylene-4-isothiazoline-3-one comprises cyclizing a 2-alkyl or aralkyl thio-1-cycloalkene-1-carboxamide in the form of its sulfoxide in an organic solvent in the presence of a acid chloride and adding to the resulting 4,5-tri or tetramethylene-4-isothiazoline-3-one hydrochloride a mineral or organic base or water so as to free the 4,5-tri or tetramethylene-4-isothiazoline-3-one in the form of a free base.