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composition for the treatment of systemic lupus erythematosus and primary glomerulonephritis
composition for the treatment of systemic lupus erythematosus and primary glomerulonephritis
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机译:用于治疗系统性红斑狼疮和原发性肾小球肾炎的药物组合物
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摘要
PURPOSE:A remedy for systemic lupus erythematosus or primary glomerulonephritis that contains a gamma globulin having the Fc part. CONSTITUTION:A gamma globulin havin the Fc part, which is obtained by subjecting gamma globulin to chemical or enzymatic treatment causing no destruction of the Fc part, thus being injected for plasmin treatment, is used as an active ingredient to given a remedy for systemic lupus erythematosus or primary glomerulonephritis. It is given intravenously, the dose is 20-100mg/kg/day as gamma globulin and continued for one to several weeks. It seems that, when the globulin reaches the lesion site, excessive amounts of the Fc part bind with the deposite to cleave the bonds between antigen-antibody, resulting in dissolution of the deposit.
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机译:目的:一种针对系统性红斑狼疮或原发性肾小球肾炎的药物,其中含有具有Fc部分的γ球蛋白。组成:丙种球蛋白具有Fc部分,该部分是通过对丙种球蛋白进行化学或酶处理而不会破坏Fc部分而获得的,因此被注射用于纤溶酶治疗,被用作有效成分治疗全身性狼疮红斑或原发性肾小球肾炎。静脉注射,剂量为20-100mg / kg /天,以丙种球蛋白的形式持续1至几周。看来,当球蛋白到达病变部位时,过量的Fc部分与被沉积物结合以切割抗原-抗体之间的键,导致沉积物溶解。
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