process for the production of 14:15 - derived metilenici of series of estrano

摘要

Compounds of the general formula IMAGE in which R' is hydrogen or a methyl radical; R is a hydroxyl, acetoxy, arylaminocarbonyloxy, alkylaminocarbonyloxy radical; Z is hydrogen or a lower alkyl, or R and Z together are oxygen. These compounds exhibit a very favorable separation of desirable contraceptive and undesirable uterine and antigonadotrophic properties.