A process for the preparation of spiro (imidiazolina-4,1 '- (2'H) -naphthalene) and spiro (chroman-4,4'-imidazolidines)

摘要

Spiro-imidazolidines of the formula: …CHEM… and the pharmaceutically acceptable salts thereof, wherein X is O, CH2 or NH; R is hydrogen, fluoro, chloro, methyl or methoxy; and Y is O or CH2. …??These compounds are useful in treatment to prevent or alleviate ocular or neuritic diabetes-associated chronic complications.