MONOCLONAL ANTIBODIES TO HUMAN BLADDER AND URETER CANCERS AND METHOD

摘要

AbstractA panel of monoclonal antibodies, produced from humanbladder tumors as immunogen, is used to diagnose thepresence of transitional cell carcinoma in patients. Thepanel is also used to identify and differentiate low gradenon-invasive papillomas from invasive life-threateningtransitional cell carcinomas, thereby enabling decisions asto the extent of bladder surgery. These mAbs can also beused as a panel for tissue typing of normal and abnormalcell specimens.