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PROCESS FOR THE PREPARATION OF PYRIDAZINE DERIVATIVES HAVING A PSYCHOTROPIC ACTION
PROCESS FOR THE PREPARATION OF PYRIDAZINE DERIVATIVES HAVING A PSYCHOTROPIC ACTION
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机译:具有拟南芥作用的哒嗪衍生物的制备方法
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PATENT APPLICATIONEntitled : Process for the preparation of pyridazine deri-vatives having a psychotropic action,In the names of : Kathleen BIZIERE, Jean-Paul KAN andCamille-Georges WERMUTH.Assignee : Société Anonyme called : SANOFIABSTRACTThe present invention relates to a process forthe preparation of 4-cyanopyridazine derivatives cor-responding to the formula below, which consists intreating an appropriately substituted 4-ethoxycarbonyl-pyridazone with aqueous ammonia, in subsequently treatingthe resulting pyridazone-4-carboxamide with phosphorusoxychloride and in reacting the 3-chloro-4-cyanopyridazinewith an amine of the formula H2N-Alk-? (I)
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