Process for the preparation of barium sulfate with increased fluidity and density suitable as a shadow producing component in X-ray contrast agents, product obtained by this process and X-ray contrast agents prepared therefrom

摘要

Barium sulfate suitable for the preparation of radiographic contrast agents of increased flowability and density is obtained by a high temperature treatment at 700 DEG to 1,200 DEG C. and preferably at 800 DEG to 1,000 DEG C. The barium sulfate so sintered is distinguished by a bulk density of 2.5 to 3 g/ml and its aqueous suspension, containing 200 g of barium sulfate per 100 ml, is distinguished by a viscosity of no more than 1,000 mPas. Radiographic contrast agents containing at least 200 g of sintered barium sulfate per 100 ml are outstandingly suitable for the difficult double contrast visualization of the stomach and gastric mucosa.