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Use of gonadoliberin and gonadoliberin agonists in the treatment of metabolic diseases due to too small a parathormone level

机译:副激素水平过低导致的性腺激素和性腺激素激动剂在代谢疾病治疗中的应用

摘要

1. Claims (for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE) Pharmaceutical formulation for parenteral administration for the treatment of metabolic disorders which may arise due to the secretion of endogenous parathyroid hormone being too low, which contains 0.5 to less than 5 mu g of gonadoliberin/single dose, or 0.05 to 0.5 mu g of a gonadoliberin agonist/single dose, for an adult of normal weight in a pharmaceutically acceptable vehicle. 1. Claims (for the Contracting State AT) Process for the preparation of a pharmaceutical formulation for parenteral use for the treatment of metabolic disorders which may arise due to the secretion of endogenous parathyroid hormone being too low, containing 0.5 to less than 5 mu g of gonadoliberin/single dose or 0.05 to 0.5 mu g of a gonadoliberin agonist/single dose, for an adult of normal weight, which comprises converting gonadoliberin or its analog, together with a pharmaceutically acceptable vehicle, into a suitable formulation form.
机译:1.索赔(针对缔约国:BE,CH,DE,FR,GB,IT,LI,LU,NL,SE)肠胃外给药的药物制剂,用于治疗由于内源性甲状旁腺分泌引起的代谢异常对于药学上可接受的赋形剂正常体重的成年人,激素水平过低,其中含有0.5至小于5μg的性腺多菌素/单剂,或0.05至0.5μg的性腺多巴素激动剂/单剂。 1.(针对缔约国AT)要求保护的方法,用于制备用于胃肠外疾病的肠胃外药物制剂,所述代谢性疾病可能是由于内源性甲状旁腺激素的分泌过低而引起的,其含量为0.5至小于5μg对于正常体重的成年人,可使用多纳多巴胺/单剂量或0.05-0.5μg的多纳多巴胺激动剂/单剂量,其包括将多纳多巴胺或其类似物与药学上可接受的载体一起转变成合适的制剂形式。

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