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L-di or tripeptides possessing a biological activity for use in human and veterinary medicines, process for their obtention and medicines containing them

机译:具有生物活性的L-di或三肽,可用于人和兽药,其获得过程以及含有它们的药物

摘要

A process for the synthesis of phosphonic di- or tripeptides of L configuration by reaction of an alpha -aminoacid or of a carboxylic dipeptide with an alpha -aminophosphonic acid or of an alpha -aminocarboxylic acid with a phosphonic dipeptide of L configuration, the reaction being carried out in the presence of an enzyme such as papain with phase separation; the invention also relates to the new products obtained and to medicines containing the said phosphonic di- or tripeptides.
机译:通过α-氨基酸或羧酸二肽与α-氨基膦酸或α-氨基羧酸与L构型的膦酸二肽反应合成L构型的膦酸二肽或三肽的方法,该反应为在酶如木瓜蛋白酶存在下进行相分离;本发明还涉及获得的新产品和含有所述膦酸二肽或三肽的药物。

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