首页> 外国专利> Improved process for the stimulation of the sex tae, therefore, and held in the form of a productive livestock from mammals as well as for the production of to their propagation suitable sperm

Improved process for the stimulation of the sex tae, therefore, and held in the form of a productive livestock from mammals as well as for the production of to their propagation suitable sperm

机译:因此,改进了刺激性行为的方法,并以哺乳动物的生产性家畜的形式保存,以及繁殖出合适的精子

摘要

The invention relates to a process for increasing the sexual activity of birds and useful domestic mammals and for preparing spermatozoa suitable to their propagation. The process of the invention comprises treating sexually mature male birds or useful domestic mammals at least twice and at most four times with 0.1 to 5 mu g/kg of body weight of a compound of the general formula (I), Glp-His-Trp-Ser-Tyr-X1-Leu-Arg-Pro-X4 (I) wherein X1 stands for a glycyl group, a natural or synthetic aminoacid or aminoacid derivative of D configuration, an -Asp-Q group of L configuration, wherein Q is attached to the alpha -carbonyl moiety of the aspartyl group and represents a C1-5 alkylamide, an arylamide, a C1-4 alkoxy or a benzyloxy group; and X4 stands for a glycylamide or a C1-4 alkylamide group, while keeping a pause of at least 30 hours and at most 72 hours between the consecutive treatments. The process of the invention can mainly be used in such large-scale breedings, where artificial insemination is employed but it can be used also for any domestic bird or cought wild-fowl and ornamental bird as well as useful domestic mammal under the conditions of the natural reproduction or artificial insemination.
机译:本发明涉及一种提高鸟类和有用的家养哺乳动物的性活动并制备适于它们繁殖的精子的方法。本发明的方法包括用0.1至5μg/ kg体重的通式(I)化合物Glp-His-Trp处理性成熟的雄禽或有用的家养哺乳动物至少两次且至多四次。 -Ser-Tyr-X1-Leu-Arg-Pro-X4(I),其中X1代表缩水甘油基,D构型的天然或合成氨基酸或氨基酸衍生物,L构型的-Asp-Q基团,其中Q为连接至天冬氨酰基的α-羰基部分并代表C 1-5烷基酰胺,芳酰胺,C 1-4烷氧基或苄氧基; X 4代表甘氨酰胺基或C 1-4烷基酰胺基,同时在连续处理之间保持至少30小时和至多72小时的停顿。本发明的方法可主要用于使用人工授精的大规模育种中,但也可用于任何家禽或人工野禽和观赏鸟以及在此条件下有用的家养哺乳动物。自然繁殖或人工授精。

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