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Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or -caprolactones
Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or -caprolactones
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机译:制备丙交酯或丙交酯与乙交酯和/或己内酯的微囊的方法
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摘要
A process for preparing polylactide (PLA) microcapsules is described and involves dissolving PLA in a mixture of two miscible organic liquids, the higher vapor pressure liquid having solvent power for PLA and the second having little or no solvent power for PLA. The solution is prepared such that it is near its saturation point for PLA. Encapsulation of dispersed core material is achieved by vaporizing the liquid having solvent power for PLA causing phase separation of the PLA, then transferring the separated dispersion to an organic liquid having no solvent power for the PLA in order to harden the encapsulating coating. The disclosed process enables forming true microcapsules or reservoir- type devices encapsulating liquid core material particularly aqueous liquid core material and oil in water emulsion or suspensions.
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