3-O-benzyl-2,4,6-tridooxy-6-iodo-alpha-D-erythro-hexopyranide useful for preparing inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase

摘要

Totally synthetic analogs of the known inhibitors of 3-hydroxy- 3- methylglutaryl coenzyme A reductase, compactin and mevinolin, are prepared from a chiral synthon derived from D-glucose which has the same chirality as the natural products.