NOVEL PYRAZOLO (3, 4-D) PYRIMIDINE, ITS PRODUCTION AND DRUG FOR TREATING BRONCHOSPASMIC AND BRONCHOCONSTRICTIVE REACTION INDUCED BY ALLERGIC DISEASE AND INFLAMMATION

摘要

Pyrazolo[3,4-d]pyrimidines of the formula I …IMAGE… in which… R1 denotes a C1- to C6-alkyl radical, a C2- to C6-alkenyl radical, a C3- to C7-cycloalkyl radical or an aryl radical,… R2 denotes a C2- to C6-alkenyl radical, a C3- to C7-cycloalkyl radical or an aralkyl or hetaralkyl radical having 1 to 6 carbon atoms in the alkyl moiety and which, if desired, is mono- or polysubstituted by halogen, C1- to C6-alkyl, hydroxyl, C1- to C6-alkoxy, C1- to C3-haloalkyl, C3- to C7-alkoxycarbonyl, aminocarbonyl, C2- to C7-alkylaminocarbonyl, C3- to C13-dialkylaminocarbonyl, cyano or C1- to C6-alkylthio and… R3 denotes hydrogen, a C2- to C6-alkyl radical which, if desired, is mono- or polysubstituted by hydroxyl, a tetrahydrofuranyl radical or a tetrahydropyranyl radical,… with the proviso that R2 cannot be unsubstituted benzyl if R1 represents the methyl group,… and their physiologically tolerable salts of inorganic or organic acids are used as medicaments for the treatment of allergic diseases and of bronchospastic and bronchoconstrictive reactions due to inflammation.