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BIOLOGICAL CATALYTIC REACTION OPERATION IN FLUIDIZED BED REACTOR OF LIQUID TWO-PHASE SYSTEM
BIOLOGICAL CATALYTIC REACTION OPERATION IN FLUIDIZED BED REACTOR OF LIQUID TWO-PHASE SYSTEM
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机译:液相两相流化床反应器中的生物催化反应操作
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摘要
A process for reacting substrates with biocatalysts in a two-phase liquid system disposed in a columnar vessel having a top portion with an exit opening and a first filter disposed therein, a bottom portion with an entrance opening and a second filter disposed therein, a feed line connecting the exit and entrance openings, and a pump disposed in the feed line. The process comprises the steps of: stirring the two-phase liquid in the columnar vessel to accelerate sedimentation and minimize accumulation of the biocatalysts in the top portion of the vessel; selectively controlling the temperature of the two-phase liquid within the vessel; drawing, with the pump, a portion of the two-phase liquid through the exit opening and first filter; and passing the drawn-off portion of the two-phase liquid through the feed line and through the entrance opening and second filter into the vessel to enhance miscibility of the individual phases of the two-phase liquid with the vessel.
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