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Analogifremgangsmaade for the preparation of 4- (naphthyl-methyl) -piperidine derivatives or pharmaceutically acceptable acid addition salts thereof as well as compounds for use as starting materials in the process
Analogifremgangsmaade for the preparation of 4- (naphthyl-methyl) -piperidine derivatives or pharmaceutically acceptable acid addition salts thereof as well as compounds for use as starting materials in the process
Novel compounds of the formula IMAGE wherein n is an integer of from 2 to 5, R is hydrogen, alkyl, alkoxy, halogen or trifluoromethyl, R1 is hydrogen, alkyl, alkoxy or halogen, X is carbonyl, hydroxymethylene or methylene, and Z is carbonyl or hydroxymethylene and their pharmaceutically acceptable acid addition salts are useful as antipsychotic agents having a low potential for extrapyramidal side effects. The novel compounds are prepared from novel intermediates of formula IMAGE or their salts wherein R and X have the meanings defined above.
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