A pharmaceutical composition containing L-3,4-dihydroxyphenylalanine (L-DOPA) as active ingredient and method of preparation of such a composition

摘要

The present invention relates to a multiple-unit-dose comprising L-dopa as pharmaceutically active compound, whereby the composition provides a release of L-dopa in accordance with a test in accordance with US Pharmacopea Standards in an artificial gastric juice having a pH of at most 1.2 of at most 20 % by weight during 1 hr, and in a phosphate buffer according to the same standard a release of at least 35 % by weight during 1 hr, and at least 80 % by weight during 3 hrs.