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process for the preparation of cholinesalicylaat containing pharmaceutical preparation and method for the preparation of a cholinesalicylaat containing complex.

机译:含胆碱水杨酸的药物制剂的制备方法和含胆碱水杨酸的复合物的制备方法。

摘要

Novel cholinesalicylate-carboxy-lower alkyl-cellulose-metal complexes are obtained by forming an aqueous solution of a carboxy-lower alkyl-cellulose and cholinesalicylate, adding a source of a physiologically tolerated, at least doubly charged, metal ion in a quantity such that a complex is formed of the components, allowing the reaction mixture to stand until it thickens, and subsequently drying it. The novel compounds are stable, pharmaceutically active, cholinesalicylate compounds.
机译:新型胆碱水杨酸-羧基-低级烷基纤维素-金属配合物是通过形成羧基低级烷基纤维素和胆碱水杨酸的水溶液,并添加一定量的生理上可耐受的,至少双电荷的金属离子而获得的。由各组分形成络合物,使反应混合物静置直至其变稠,然后干燥。新化合物是稳定的,具有药物活性的胆碱水杨酸酯化合物。

著录项

  • 公开/公告号NL183821B

    专利类型

  • 公开/公告日1988-09-01

    原文格式PDF

  • 申请/专利权人 MUNDIPHARMA A.G. TE BAZEL ZWITSERLAND.;

    申请/专利号NL19770000514

  • 发明设计人

    申请日1977-01-19

  • 分类号C07C65/10;A61K31/725;C07C91/26;C08B11/12;

  • 国家 NL

  • 入库时间 2022-08-22 06:59:41

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