Anvendelse af heparin, N-desulfateret, N-acetyleret heparin eller O-desulfateret, N-acetyleret heparin til fremstilling af et farmaceutisk præparat, som er effektivt over for autoimmune sygdomme, til lindring af sådanne sygdomme og til behandling af autoimmune sygdomme i pattedyr, herunder mennesker, og til hindring eller forsinkelse af allotransplantatudstødelse

摘要

The invention relates to means for preventing or for delaying the rejection of allografts in humans and for the alleviation of and for treating autoimmune diseases in humans. The pharmaceutical compositions which are suitable to attain the above ends ard based on heparin, on N-desulfated, on N-acetylated heparin or other suitable derivatives of heparin. The dosage which is effective is one which is substantially lower than that required for obtaining an anticoagulant effect in mammals. It is generally of the order of about 1 per cent to about 10 per cent of the anti-coagulant effective dosage of such compounds.