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PROCESS FOR OBTAINING 4'-DEOXYDAUNORUBICIN AND 4'-DEOXYDOXORUBICIN
PROCESS FOR OBTAINING 4'-DEOXYDAUNORUBICIN AND 4'-DEOXYDOXORUBICIN
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机译:获得4'-去氧柔红霉素和4'-去氧柔红霉素的过程
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摘要
A new process for the preparation of the known 4'-deoxydaunorubicin and 4'-deoxydoxorubicin is disclosed. The used starting material is 4'-eip-N-trifluoroacetyldaunorubicin which is converted into 4'-deoxy-4'-iodo-N-trifluoroacetyl-daunorubicin from which 4'-deoxy-daunorubicin can be reductively obtained and eventually transformed, by known methods, into 4'-deoxy-doxorubicin.
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