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USE OF PYRIDOXINE DERIVATIVES IN THE PREVENTION AND TREATMENT OF HYPERLIPIDAEMIA AND ATHEROSCLEROSIS
USE OF PYRIDOXINE DERIVATIVES IN THE PREVENTION AND TREATMENT OF HYPERLIPIDAEMIA AND ATHEROSCLEROSIS
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机译:乙氧嘧啶衍生物在高脂血症和动脉粥样硬化的预防和治疗中的应用
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摘要
Pyridoxine derivatives and their salts, in particular pyridoxal, pyridoxal phosphate, pyridoxamine and pyridoxamine phosphate, are used in the prophylaxis and treatment of hyperlipidaemia and atherosclerosis. Exceptions are pyridoxine-5'-phosphoric acid glutamate and aspartate, which are described in DE 2,461,742 C2. Natural, highly compatible, chemically unambiguously described and adequately stable substances having good activity for long term treatments are thereby made available. The buccal administration form and enteric-resistant forms have proved particularly suitable.
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机译:吡rid醇衍生物及其盐,特别是吡ido醛,磷酸吡ido醛,吡ido胺和磷酸吡ido胺被用于预防和治疗高脂血症和动脉粥样硬化。 DE 2,461,742 C2中描述了吡pyr醇-5'-磷酸谷氨酸和天冬氨酸的例外。由此可获得天然的,高度相容的,化学上明确描述的,并且具有长期治疗活性的足够稳定的物质。口腔给药形式和抗肠溶形式已被证明是特别合适的。
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