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ergolinderivat, still for their framstellning and pharmaceutical compositions of the governments
ergolinderivat, still for their framstellning and pharmaceutical compositions of the governments
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机译:ergolinderivat,仍然是因为他们对政府的批评和药物成分
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摘要
There are provided ergoline derivatives of formula IMAGE wherein R1=H, CH3; R2=H or halogen atom, or CH3,CN, alkyl- or phenyl-thio; R3=H, OCH3; R4=C1-C4 hydrocarbon group; X=O, S, NH; A=CO, SO2; B=C1-C4 hydrocarbon group, aryl, aralkyl, heterocyclic ring group, alkoxy, aryloxy; n=0, 1, 2; and pharmaceutically acceptable salts thereof. A process for preparing said compounds is also provided. The compounds show anti-hypertensive activity and are active on the gastroenteric system.
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机译:提供了式的麦角灵衍生物,其中R1 = H,CH3; R 2 = H或卤素原子,或CH 3,CN,烷基或苯基硫基; R3 = H,OCH3; R4 = C1-C4烃基; X = O,S,NH; A = CO,SO2; B = C1-C4烃基,芳基,芳烷基,杂环基,烷氧基,芳氧基; n = 0,1,2;及其药学上可接受的盐。还提供了制备所述化合物的方法。该化合物具有抗高血压活性,对胃肠系统有活性。
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