NEW ANTIBIOTICS, METHOD FOR THEIR PRODUCTION, THEIR USE AS MEDICINAL PRODUCTS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION.

摘要

New antibiotics of the formula IMAGE in which X is O or N-CO-NH2, R is the radical of an aminoacid other than serine, an oligopeptide other than HyoHyoHyoSer or a derivative thereof on the free amino group, or a radical from the group comprising HyoSer, HyoHyoSer, HyoHyoHyoAla, HyoHyoHyoThr, Hyo, HyoHyo or HyoHyoHyo, and Hyo is N5-acetyl-N5-hydroxy-L-ornithine. The intermediate wherein R is H is also new as is the tripeptide IMAGE