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A method for producing tetrabasicos acids for use in the therapy of Human and Veterinary Medicine.
A method for producing tetrabasicos acids for use in the therapy of Human and Veterinary Medicine.
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机译:一种生产用于人体和兽医学治疗的四元酸的方法。
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摘要
Procedure for obtaining tetrabasicos acids of formula (i), their bases non-toxic physiologically compatible, and hydrolysable Esters.Diclorometilo comprises reacting an ether of formula (R1 - X - N - ochcl2 ch2ch2), two molar Equivalents of a trialquilo phosphite in the presence of a Lewis acid, or a Salt alcalimetalica two molar Equivalents of a dialkyl phosphite to form a compound of formula (i) In which X is Oxygen or sulfur, R1 and R2 may be several types of radicals and N is 0 - 2.Obtaining reaction can also be performed in two stages. These compounds have applications for the pharmacological treatment of processes with abnormal of Calcium balance.
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