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3-TETRAHYDRONAPHTHYL-4-HYDROXYCOUMARIN COMPOUNDS HAVING ANTI-COAGULATING PROPERTIES
3-TETRAHYDRONAPHTHYL-4-HYDROXYCOUMARIN COMPOUNDS HAVING ANTI-COAGULATING PROPERTIES
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机译:具有抗凝血性能的3-四氢萘基-4-羟基香豆素化合物
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K 1870AbstractCompounds having blood-anticoagulant properties of thegeneral molecular formula: (II), in which Z represents a halogen atom, preferably a chlorineatom, and n is 0, 1 or 2 and R4 represents either (1) a groupingwhich ccmprises a phenylene radical attached directly orindirectly to the tetralin ring and having in the para position(with respect to such attachment) an electron-withdrawing atomor group whose rotational volume substantially does not exceedthat of a phenyl group and which forms together with saidphenylene radical a polarisable structure, or (2) a groupingselected from: or or BN23.006or (3) a grouping which comprises a phenylene radicalattached directly to the tetralin ring and having in thepara position (with respect to such attachment) asubstituted furanyl or thiophenyl radical attached theretodirectly or through oxygen and/or methylene, said furanylor thiophenyl radical having such an electron-withdrawing atomor group as a substituent in a position forming with the furanylor thiophenyl radical a polarisable structure, Compounds of thetype (1) in which R4 contains two phenylene radicals linkedessentially linearly by an aliphatic chain comprising amethylene radical or radicals and optionally at least one oxygenor sulphur atom being preferred.Also included are the processes for the preparation of suchcompound; rodenticidal compositions containing them; and amethod for controlling rodents by applying such a composition.BN11.008
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