2.6 - dihydroxymethylpyridin bis (n - methylcarbamate) amp; amp; gamma; amp; amp; darr; 2 amp; amp; darr; kristallmodifikation this containing medicines and methods for manufacturing the same, and 2.6 dihydroxymethylpyridinbis - (n - methylcarbamate) dihydrate the amp; amp; gamma; amp; amp; darr; 1 amp; amp; darr; kristallmodifik and processes for the manufacture of the latter.

摘要

2,6-Dihydroxymethylpyridine-bis-(N-methylcarbamate) in the gamma 2 modification is obtained from 2,6-dihydroxymethylpyridine hydrochloride using methyl isocyanate, the purification being effected by recrystallisation from an alcohol-water mixture and the drying being carried out at 50-100 DEG C. The product thus obtained, which is employed in the therapy of vascular diseases, can easily be made into tablets.