SPECIFIC ANTIBODY TO THE NATIVE FORM OF 2'5'-OLIGONUCLEOTIDES, THE METHOD OF PREPARATION AND THE USE AS REAGENTS IN IMMUNOASSAYS OR FOR BINDING 2'5'-OLIGONUCLEOTIDES IN BIOLOGICAL SYSTEMS

摘要

PCT No. PCT/EP84/00062 Sec. 371 Date Nov. 9, 1984 Sec. 102(e) Date Nov. 9, 1984 PCT Filed Mar. 6, 1984 PCT Pub. No. WO84/03444 PCT Pub. Date Sep. 13, 1984.A new specific antibody to 5'-terminal mono-, di- or triphosphorylated (2'-5')adenyl-adenosine oligonucleotides and a method of producing it have been found. The antibody can be used for the quantitative analysis of the oligonucleotides mentioned above in any one of the well known methods of immunological analysis.