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Novel polyfunctional derivatives of 2-methylbutanoic acid and novel process for the preparation of these and other 2-methylbutanoic acid derivatives

机译:2-甲基丁酸的新型多官能衍生物和制备这些及其他2-甲基丁酸衍生物的新方法

摘要

2,4-Disubstituted and 2,3,4-trisubstituted 2-methylbutanoic acid derivatives of the general formula (I) IMAGE in which R1 stands for a straight or branched alkyl group having 1-9 carbon atoms, for a cycloalkyl group which has 5-7 carbon atoms in the ring and is optionally mono- or disubstituted by alkyl having 1-4 carbon atoms, or for a phenylalkyl group having 1-3 carbon atoms in the alkyl moiety, which can be substituted in the ring by alkyl and/or alkoxy each having 1 or 2 carbon atoms, R2 denotes hydrogen, a straight or branched alkyl group having 1-4 carbon atoms, an aryl group optionally substituted by alkyl or alkoxy having 1 or 2 carbon atoms, an alkanoyl group having 1-4 carbon atoms or a group IMAGE in which the meaning of R1 is the same as above, and R3 stands for an alkanoyl group having 1-4 carbon atoms, for an aryl group which is optionally substituted by alkyl or alkoxy having 1 or 2 carbon atoms, for a cyano group or a group IMAGE in which the meaning of R1 is the same as above with the restriction that if R3 = CN R2 has a meaning other than hydrogen, and a process for their preparation.v
机译:通式(I)的2,4-二取代和2,3,4-三取代的2-甲基丁酸衍生物其中R 1代表具有1-9个碳原子的直链或支链烷基。在环中具有5-7个碳原子并且任选地被具有1-4个碳原子的烷基单或二取代的环烷基,或者对于在烷基部分中具有1-3个碳原子的苯基烷基,其可以被取代为在环上分别具有1或2个碳原子的烷基和/或烷氧基,R 2表示氢,具有1-4个碳原子的直链或支链烷基,任选被具有1或2个碳原子的烷基或烷氧基取代的芳基原子,具有1-4个碳原子的烷酰基或R 1的含义与上述相同的基团,并且R 3代表具有1-4个碳原子的烷酰基。对于氰基或基团,其任选地被具有1或2个碳原子的烷基或烷氧基取代的芳基R 1的基团与上述相同,但是如果R 3 = CN,则R 2具有除氢以外的含义及其制备方法。

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