首页> 外国专利> New tetralines, 1995 of preparation, their use for the preparation of anthracyclinones and new glycosides (anthracyclines) obtained from these anthracyclinones

New tetralines, 1995 of preparation, their use for the preparation of anthracyclinones and new glycosides (anthracyclines) obtained from these anthracyclinones

机译:1995年制备的新四线虫类,其用于制备蒽环素和从这些蒽环素中获得的新糖苷(蒽环类)的用途

摘要

The present invention relates to new tetralins and their use for the preparation of anthracyclinones and anthracyclins. These tetralins contain at least one chiral carbon atom and correspond to the formula (V) below: IMAGE (V) in which: R1 and R2 denote a hydrogen atom, or a halogen atom or the group OCH3, provided that one of the two substituents (R1 or R2) must denote OCH3, and R3 denotes a hydrogen atom or the OR' group, R' being hydrogen or a hydroxyl-protecting group. Application: synthesis of glycosides of great therapeutic value.
机译:本发明涉及新的四氢化萘及其在制备蒽环素和蒽环素中的用途。这些四氢化萘含有至少一个手性碳原子,并且对应于下式(V):(V)其中:R 1和R 2表示氢原子,或卤素原子或基团OCH 3,条件是两个取代基(R1或R2)必须表示OCH3,R3表示氢原子或OR'基,R'为氢或羟基保护基。应用:合成具有极高治疗价值的糖苷。

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