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Purifications of B-cell inducing factor (BIF) and B-cell growth factor (BGF)
Purifications of B-cell inducing factor (BIF) and B-cell growth factor (BGF)
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机译:B细胞诱导因子(BIF)和B细胞生长因子(BGF)的纯化
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摘要
Highly purified T cell replacing factor (TRF or BIF) essentially free of IL-2 and Interferon activities is obtained in the invention. BIF is useful for treatment of immunoregulatory disorders and/or stimulation of production of immunoglobulins. A method for production of BIF and BGF is described.PPB cell lines for BIF assays are described as well as an assay for B cell receptor variants and a method for obtaining B cell variants from a variety of source materials.
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机译:在本发明中获得了基本上没有IL-2和干扰素活性的高度纯化的T细胞替代因子(TRF或BIF)。 BIF可用于治疗免疫调节异常和/或刺激免疫球蛋白的产生。描述了产生BIF和BGF的方法。描述了用于BIF测定的P> P B细胞系,以及用于B细胞受体变体的测定和从多种来源获得B细胞变体的方法。
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