A method of inhibiting cataract formation occasioned by the oxidative cross-linking of proteinaceous material in the lens fiber of the eye of a mammal comprising the topical administration of an effective antioxidant amount, to the eye of said mammal in need of the same, of a compound of the formula: ##STR1## wherein R is phenyl or phenyl substituted lower alkyl, the phenyl group of each being unsubstituted or substituted by halo, lower alkyl, lower alkoxy, trifluoromethyl, nitro, di- loweralkylamino, cyano, carboxy, methylenedioxy, loweralkoxycarbonyl, carboxyloweralkyl, or loweralkoxycarbonyl-lower alkyl, or R is cycloalkyl of 5 to 10 carbon atoms; andPPR.sub.1 and R.sub.2 are independently hydrogen, halo, lower alkyl, lower alkoxy, hydroxy, trifluoromethyl, or nitro or R.sub.1 and R.sub.2 taken together are methylenedioxy.
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机译：一种抑制白内障形成的方法，所述方法由哺乳动物的眼睛的晶状体纤维中的蛋白质材料的氧化交联引起，其包括向需要该治疗的所述哺乳动物的眼睛局部施用有效抗氧化剂。式中的化合物：其中R是苯基或苯基取代的低级烷基，每个苯基未被取代或被卤素，低级烷基，低级烷氧基，三氟甲基，硝基，二-低级烷基氨基，氰基，羧基取代或亚甲基二氧基，低级烷氧基羰基，羧基低级烷基或低级烷氧基羰基-低级烷基，或R为5至10个碳原子的环烷基; P 1和R 2独立地是氢，卤素，低级烷基，低级烷氧基，羟基，三氟甲基或硝基，或R 1和R 2一起是亚甲二氧基。
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