NOVEL ACONITINE BASED COMPOUND AND ANALGETIC AND ANTI-INFLAMMATORY AGENT CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT

摘要

NEW MATERIAL:A compound expressed by formula I (R1 represents benzoyl or anisoyl; R2 represents methyl or ethyl; R3 represents benzoyl or anisoyl; R4 represents acetyl). EXAMPLE:3-Benzoyl mesaconitine. USE:An analgesic and anti-inflammatory agent. PREPARATION:The hydroxyl group at the 3-position of mesaconitine expressed by formula II, aconitine expressed by formula III or jesaconitine expressed by formula IV is benzoylated or anisoylated by a conventional method.