DRUG PREPARATION OF COMPLEX OF POLYRIBOINOSINIC ACID, POLYRIBOCYTIDYLIC ACID AND POLY-L-LYSINE

摘要

PURPOSE:To obtain a freeze-dried drug preparation having improved solubility and stability after the storage over a long period and useful as an antitumor agent, by adding a soluble protein and polysaccharide as constituent components to a polyriboinosinic acid.polyribocytidylic acid.poly-L-lysine complex. CONSTITUTION:A freeze-dried drug preparation composed of a polyriboinosinic acid.polyribocytidylic acid.poly-L-lysine complex is added with a soluble protein and/or polysaccharide as constituent components. The soluble protein is gelatin, collagen or serum albumin or a mixture of two or more of the above proteins. The polysaccharide is dextrin, dextran, chondroitin sulfate or a mixture of two or more of the polysaccharides. The amounts of the soluble protein and the polysaccharide are preferably 0.3-30pts.wt., and 0.1-30pts.wt. per 1pt.wt. of the complex, respectively.