QUINOLYPYRIMIDINE DERIVATIVE, ITS PRODUCTION AND PLANT BLIGHT CONTROLLING AGENT CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT

摘要

NEW MATERIAL:The compound of formula I (R1 and R2 are H or methyl; R3 is lower alkyl; R4 is H or lower alkyl; R5 is H, lower alkoxy or lower alkyl) and its salt. EXAMPLE:4-Methyl-2-(2-quinolyl)pyrimidine. USE:A plant blight controlling agent. PREPARATION:A 2-amidinoquinoline derivative of formula II or its salt is made to react with a beta-oxoacetal derivative of formula III (R6 is lower alkyl) preferably at an equivalent ratio of 1:1-1.5 in the presence of a base (e.g. sodium methoxide) preferably at 50-150 deg.C for 1-6hr. The reaction is carried out usually in a solvent such a methanol, THF and DMF, etc.