substituted dicarboxylsyre - bis (3,5 - dicarbamoyl - 2,4,6 - trijodanilider), method for manufacture thereof, and roentgenkontrastmidler containing these

摘要

Novel substituted dicarboxylic acid bis(3,5-dicarbamoyl- 2,4,6-triiodoanilides) of the general formula …IMAGE… in which… R1 denotes a hydrogen atom, a C1-C4-alkyl radical or R2,… R2 denotes a straight-chain or branched-chain C2-C8-mono- or polyhydroxyalkyl radical,… R3 denotes a hydrogen atom, a C1-C4-alkyl radical or R2,… R4 denotes a hydrogen atom or a C1-C4-alkyl radical and… n = 1 or 2. …??Owing to their good pharmacological and physicochemical properties, the novel non-ionic compounds of the formula I are outstandingly suitable as radio-opaque substances in X-ray contrast agents for use in all application areas of X-ray contrast agents.