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PROCESS FOR PRODUCING NEW CARBAMOYL-OXY-ALKYL-CARBOXY-LIC ACID DERIVATIVES
PROCESS FOR PRODUCING NEW CARBAMOYL-OXY-ALKYL-CARBOXY-LIC ACID DERIVATIVES
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机译:制备新的氨基甲酰-氧-烷基-羧酸-丙烯酸衍生物的方法
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摘要
A process for preparing a 2-carbamoyloxyalkyl-1,4-dihydropyridine derivative represented by the general formula: IMAGE (I) which comprises: (a) reacting a 3-amino-3-carbamoyloxyalkylacrylic acid derivative represented by the general formula: IMAGE (II) with a benzylidene compound represented by the general formula: IMAGE (III) (b) reacting the 3-amino-3-carbamoyloxyalkylacrylic acid derivative of the general formula II with an aldehyde compound represented by the general formula: IMAGE (IV) and a beta -keto-ester compound represented by the general formula: R4-CO-CH2-COOR2 (V) (c) reacting a 3-carbamoyloxyalkylpropiolic acid derivative represented by the general formula: IMAGE (VI) with the benzylidene compound of the general formula III and ammonia or its sa or (d) reacting the 3-carbamoyloyalkylpropiolic acid derivative of the general formula VI with the aldehyde compound of the general formula IV, the beta -keto-ester compound of the general formula V and ammonia or its salt.
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