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AZAPROSTACYCLINS, PROCESS FOR THEIR MANUFACTURE AND THEIR PHARMACEUTICAL USE
AZAPROSTACYCLINS, PROCESS FOR THEIR MANUFACTURE AND THEIR PHARMACEUTICAL USE
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机译:氮杂前青素及其制造工艺和药物使用
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摘要
Azaprostacyclins of Formula I IMAGE (I) wherein R1 is hydrogen, alkyl, cycloalkyl, aryl, a heterocyclic residue, or a phenacyl residue optionally substituted on the phenyl ring by bromine, phenyl, alkoxy, or dialkoxy, W is a free or functionally modified carbonyl group or a IMAGE wherein R8 is hydrogen or alkyl of 1-5 carbon atoms and R9 is hydrogen or a readily cleavable ether or acyl residue and wherein the OR9-group can be in the alpha - or beta -position, R2 is a free or functionally modified hydroxy group.
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机译:式I(I)的氮杂前环素,其中R 1是氢,烷基,环烷基,芳基,杂环残基或苯环上的任选被溴,苯基,烷氧基或二烷氧基取代的苯甲酰基,W是游离的或功能性修饰的羰基或,其中R8为氢或1-5个碳原子的烷基,R9为氢或易于裂解的醚或酰基残基,且其中OR9-基可位于α-或β-位置, R 2是游离的或官能改性的羟基。
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