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DNA CONSTRUCTS CONTAINING A KLUYVEROMYCES ALPHAFACTOR LEADER SEQUENCE FOR DIRECTING SECRETION OF HETEROLOGOUS POLYPEPTIDES
DNA CONSTRUCTS CONTAINING A KLUYVEROMYCES ALPHAFACTOR LEADER SEQUENCE FOR DIRECTING SECRETION OF HETEROLOGOUS POLYPEPTIDES
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机译:包含克鲁维酵母多态性引物序列的DNA构建物,用于指导杂种多肽的分泌
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摘要
DNA constructs that are useful for providing secretory expression of heterologous polypeptides in yeast comprising a DNA sequence that includes a Kluyveromyces alpha -factor leader sequence linked to the heterologous polypeptide by a yeast processing signal. Constructs employing the K. lactis alpha -factor leader and processing signal sequences, with and without spacer, linked to prochymosin are exemplified.
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