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4,5,6,7 - tetrahydrothieno (2,3 - (c) and (3.2) pyridinederivaten with anti thrombosis, anti platelet and anti aggratie adhesions of erythrocyte effect.method for the preparation thereof and pharmaceutical preparations containing them.
4,5,6,7 - tetrahydrothieno (2,3 - (c) and (3.2) pyridinederivaten with anti thrombosis, anti platelet and anti aggratie adhesions of erythrocyte effect.method for the preparation thereof and pharmaceutical preparations containing them.
This invention relates to 4,5,6,7-tetrahydro-thieno[2,3-c]- and [3,2-c]-pyridines having the formulae: IMAGE (I) and +tr IMAGE (II) in which R1 is selected from hydrogen and halogen; R2 is selected from hydrogen and hydroxy; R3 and R4, which may be the same or different, are each selected from hydrogen, C1-6 alkyl, phenylalkyl having 1-6 carbon atoms in the alkyl moiety, and phenyl-C1-6alkyl substituted on the phenyl nucleus with at least a substituent selected from halogen, C1-6 alkyl, C1-6 alkoxy, hydroxy, nitro, cyano and trifluoromethyl; and their acid addition salts.
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机译:本发明涉及具有下式的4,5,6,7-四氢噻吩并[2,3-c]-和[3,2-c]-吡啶:(IMAGE)(I)和+ tr ( II)其中R1选自氢和卤素; R 2选自氢和羟基; R 3和R 4可以相同或不同,各自选自氢,C 1-6烷基,在烷基部分具有1-6个碳原子的苯基烷基,和在苯基核上被至少一个取代的苯基-C 1-6烷基。选自卤素,C 1-6烷基,C 1-6烷氧基,羟基,硝基,氰基和三氟甲基的取代基;及其酸加成盐。
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