首页> 外国专利> 4,5,6,7 - tetrahydrothieno (2,3 - (c) and (3.2) pyridinederivaten with anti thrombosis, anti platelet and anti aggratie adhesions of erythrocyte effect.method for the preparation thereof and pharmaceutical preparations containing them.

4,5,6,7 - tetrahydrothieno (2,3 - (c) and (3.2) pyridinederivaten with anti thrombosis, anti platelet and anti aggratie adhesions of erythrocyte effect.method for the preparation thereof and pharmaceutical preparations containing them.

机译:4,5,6,7-四氢噻吩并(2,3-(c)和(3.2)吡啶衍生物具有抗血栓形成,抗血小板和抗血红细胞粘附的作用。其制备方法和含有它们的药物制剂。

摘要

This invention relates to 4,5,6,7-tetrahydro-thieno[2,3-c]- and [3,2-c]-pyridines having the formulae: IMAGE (I) and +tr IMAGE (II) in which R1 is selected from hydrogen and halogen; R2 is selected from hydrogen and hydroxy; R3 and R4, which may be the same or different, are each selected from hydrogen, C1-6 alkyl, phenylalkyl having 1-6 carbon atoms in the alkyl moiety, and phenyl-C1-6alkyl substituted on the phenyl nucleus with at least a substituent selected from halogen, C1-6 alkyl, C1-6 alkoxy, hydroxy, nitro, cyano and trifluoromethyl; and their acid addition salts.
机译:本发明涉及具有下式的4,5,6,7-四氢噻吩并[2,3-c]-和[3,2-c]-吡啶:(IMAGE)(I)和+ tr ( II)其中R1选自氢和卤素; R 2选自氢和羟基; R 3和R 4可以相同或不同,各自选自氢,C 1-6烷基,在烷基部分具有1-6个碳原子的苯基烷基,和在苯基核上被至少一个取代的苯基-C 1-6烷基。选自卤素,C 1-6烷基,C 1-6烷氧基,羟基,硝基,氰基和三氟甲基的取代基;及其酸加成盐。

著录项

  • 公开/公告号NL184220C

    专利类型

  • 公开/公告日1989-05-16

    原文格式PDF

  • 申请/专利权人 SOCIETE DITE: PARCOR TE PARIJS FRANKRIJK.;

    申请/专利号NL19780000034

  • 发明设计人

    申请日1978-01-02

  • 分类号C07D495/04;A61K31/445;

  • 国家 NL

  • 入库时间 2022-08-22 06:38:53

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