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ornithine and arginine salts of chetoacidi branched chain and their use in the treatment of liver and kidney dysfunction.

机译:鸟尿酸和鸟氨酸精氨酸盐的支链酸及其在治疗肝肾功能障碍中的用途。

摘要

Novel compounds are prepared by reacting ornithine or arginine with alpha keto analogs of branched chain essential amino acids, namely valine, leucine and isoleucine. The compounds are useful either individually or as a mixture in the treatment of hepatic disorders which are characterized by hyperammonemia and portal systemic encephalopathy. Use of these compounds in treatment of renal failure also appears promising.
机译:通过使鸟氨酸或精氨酸与支链必需氨基酸,即缬氨酸,亮氨酸和异亮氨酸的α-酮类似物反应来制备新型化合物。这些化合物可以单独使用或作为混合物用于治疗以高氨血症和门脉系统性脑病为特征的肝病。这些化合物在治疗肾衰竭中的应用似乎也很有希望。

著录项

  • 公开/公告号IT1202904B

    专利类型

  • 公开/公告日1989-02-15

    原文格式PDF

  • 申请/专利权人 THE JOHNS HOPKINS UNIVERSITY;

    申请/专利号IT19790021071

  • 发明设计人

    申请日1979-03-16

  • 分类号A61K;

  • 国家 IT

  • 入库时间 2022-08-22 06:37:34

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