some benzazocinon and benzazoninon derivatives, processes for their manufacture, pharmaceutical praeparate containing these compounds, and their therapeutic use.

摘要

Variously substituted 1-carboxymethyl-3-(carboxymethylamino)-benzazocin-2-one and benzazonin-2-one derivatives are disclosed as angiotensin converting enzyme inhibitors and antihypertensive agents. Synthesis of, pharmaceutical compositions and methods of treatment utilizing such compounds are included.